BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway

In our previous study, we demonstrated that the BRCC2 (breast cancer cell 2) gene is a proapoptotic molecule that interacts with Bcl-X(L). BRCC2 downregulation is associated with poor disease-free and overall survival in breast cancer. In this study, we aimed to investigate the role of BRCC2 in tumo...

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Detalles Bibliográficos
Autores principales: Li, X, Kong, X, Wang, Y, Yang, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763451/
https://www.ncbi.nlm.nih.gov/pubmed/23928696
http://dx.doi.org/10.1038/cddis.2013.290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763451/
https://www.ncbi.nlm.nih.gov/pubmed/23928696
http://dx.doi.org/10.1038/cddis.2013.290

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