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Enhancer of zeste homolog 2 activates wnt signaling through downregulating CXXC finger protein 4

Through silencing tumor suppressor genes, epigenetic changes can activate signaling pathways important to cancer development. In this report, we found an epigenetic contribution to the aberrant activation of wnt signaling in human gastric cancer. CXXC4 (CXXC finger protein 4) was identified as a nov...

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Detalles Bibliográficos
Autores principales: Lu, H, Sun, J, Wang, F, Feng, L, Ma, Y, Shen, Q, Jiang, Z, Sun, X, Wang, X, Jin, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763454/
https://www.ncbi.nlm.nih.gov/pubmed/23949225
http://dx.doi.org/10.1038/cddis.2013.293