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GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in rats

Global cerebral ischemia/reperfusion (I/R) facilitates the activation of procaspase-3 and promotes apoptosis in hippocampus. But the mechanisms have remained uncharacterized. Protein S-nitrosylation and denitrosylation is an important reversible posttranslational modification, which is a common mech...

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Detalles Bibliográficos
Autores principales: Sun, N, Hao, J-R, Li, X-Y, Yin, X-H, Zong, Y-Y, Zhang, G-Y, Gao, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763460/
https://www.ncbi.nlm.nih.gov/pubmed/23949220
http://dx.doi.org/10.1038/cddis.2013.299