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Conservation of mRNA secondary structures may filter out mutations in Escherichia coli evolution

Recent reports indicate that mutations in viral genomes tend to preserve RNA secondary structure, and those mutations that disrupt secondary structural elements may reduce gene expression levels, thereby serving as a functional knockout. In this article, we explore the conservation of secondary stru...

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Detalles Bibliográficos
Autores principales: Chursov, Andrey, Frishman, Dmitrij, Shneider, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763529/
https://www.ncbi.nlm.nih.gov/pubmed/23783573
http://dx.doi.org/10.1093/nar/gkt507