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Conservation of mRNA secondary structures may filter out mutations in Escherichia coli evolution
Recent reports indicate that mutations in viral genomes tend to preserve RNA secondary structure, and those mutations that disrupt secondary structural elements may reduce gene expression levels, thereby serving as a functional knockout. In this article, we explore the conservation of secondary stru...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763529/ https://www.ncbi.nlm.nih.gov/pubmed/23783573 http://dx.doi.org/10.1093/nar/gkt507 |