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A new telomerase RNA element that is critical for telomere elongation

The stability of chromosome ends, the telomeres, is dependent on the ribonucleoprotein telomerase. In vitro, telomerase requires at least one RNA molecule and a reverse transcriptase-like protein. However, for telomere homeostasis in vivo, additional proteins are required. Telomerase RNAs of differe...

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Detalles Bibliográficos
Autores principales: Laterreur, Nancy, Eschbach, Sébastien H., Lafontaine, Daniel A., Wellinger, Raymund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763530/
https://www.ncbi.nlm.nih.gov/pubmed/23783570
http://dx.doi.org/10.1093/nar/gkt514