Silencing subtelomeric VSGs by Trypanosoma brucei RAP1 at the insect stage involves chromatin structure changes

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Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen variant surface glycoprotein (VSG) to evade mammalian host immune responses at the bloodstream form (BF) stage. Monoallelic expression of BF Expression Site (BES)-linked VSGs and silencing of met...

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Detalles Bibliográficos
Autores principales: Pandya, Unnati M., Sandhu, Ranjodh, Li, Bibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763547/
https://www.ncbi.nlm.nih.gov/pubmed/23804762
http://dx.doi.org/10.1093/nar/gkt562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763547/
https://www.ncbi.nlm.nih.gov/pubmed/23804762
http://dx.doi.org/10.1093/nar/gkt562

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