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Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA
Discovery of the TET/JBP family of dioxygenases that modify bases in DNA has sparked considerable interest in novel DNA base modifications and their biological roles. Using sensitive sequence and structure analyses combined with contextual information from comparative genomics, we computationally ch...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763556/ https://www.ncbi.nlm.nih.gov/pubmed/23814188 http://dx.doi.org/10.1093/nar/gkt573 |