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Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA

Discovery of the TET/JBP family of dioxygenases that modify bases in DNA has sparked considerable interest in novel DNA base modifications and their biological roles. Using sensitive sequence and structure analyses combined with contextual information from comparative genomics, we computationally ch...

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Detalles Bibliográficos
Autores principales: Iyer, Lakshminarayan M., Zhang, Dapeng, Maxwell Burroughs, A., Aravind, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763556/
https://www.ncbi.nlm.nih.gov/pubmed/23814188
http://dx.doi.org/10.1093/nar/gkt573