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A versatile microsatellite instability reporter system in human cells

Here, we report the investigation of microsatellite instability (MSI) in human cells with a newly developed reporter system based on fluorescence. We composed a vector into which microsatellites of different lengths and nucleotide composition can be introduced between a functional copy of the fluore...

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Detalles Bibliográficos
Autores principales: Koole, Wouter, Schäfer, Henning S., Agami, Reuven, van Haaften, Gijs, Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763563/
https://www.ncbi.nlm.nih.gov/pubmed/23861444
http://dx.doi.org/10.1093/nar/gkt615