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Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways

Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis, especially to the lungs. Patients diagnosed with chondrosarcoma have poor prognosis. Berberine, an active component of the Ranunculaceae and Papaveraceae families of plant, has b...

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Detalles Bibliográficos
Autores principales: Wu, Chi-Ming, Li, Te-Mao, Tan, Tzu-Wei, Fong, Yi-Chin, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763569/
https://www.ncbi.nlm.nih.gov/pubmed/24027594
http://dx.doi.org/10.1155/2013/423164