RNA pathogenesis via Toll-like receptor-activated inflammation in expanded repeat neurodegenerative diseases

Previously, we hypothesized that an RNA-based pathogenic pathway has a causal role in the dominantly inherited unstable expanded repeat neurodegenerative diseases. In support of this hypothesis we, and others, have characterized rCAG.rCUG(100) repeat double-strand RNA (dsRNA) as a previously unident...

Descripción completa

Detalles Bibliográficos
Autores principales: Richards, Robert I., Samaraweera, Saumya E., van Eyk, Clare L., O’Keefe, Louise V., Suter, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763583/
https://www.ncbi.nlm.nih.gov/pubmed/24046729
http://dx.doi.org/10.3389/fnmol.2013.00025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763583/
https://www.ncbi.nlm.nih.gov/pubmed/24046729
http://dx.doi.org/10.3389/fnmol.2013.00025

Ejemplares similares