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Effect of Co-Administration of Rivaroxaban and Clopidogrel on Bleeding Time, Pharmacodynamics and Pharmacokinetics: A Phase I Study

Dual antiplatelet therapy with acetylsalicylic acid and a thienopyridine, such as clopidogrel, is effective for the secondary prevention of cardiovascular events in patients with acute coronary syndrome, but there is still a substantial residual risk of recurrence. Although anticoagulant therapy wit...

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Detalles Bibliográficos
Autores principales: Kubitza, Dagmar, Becka, Michael, Mück, Wolfgang, Schwers, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763640/
https://www.ncbi.nlm.nih.gov/pubmed/24281379
http://dx.doi.org/10.3390/ph5030279