Sphingosine 1-Phosphate Receptor 1 as a Useful Target for Treatment of Multiple Sclerosis

Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, is generated from sphingosine by sphingosine kinases and binds five known cell surface receptors. S1P receptor 1 (S1P(1)) plays an essential role in lymphocyte egress from secondary lymphoid organs (SLO), as evinced by the inability of lymp...

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Detalles Bibliográficos
Autores principales: Chiba, Kenji, Adachi, Kunitomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763654/
https://www.ncbi.nlm.nih.gov/pubmed/24281561
http://dx.doi.org/10.3390/ph5050514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763654/
https://www.ncbi.nlm.nih.gov/pubmed/24281561
http://dx.doi.org/10.3390/ph5050514

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