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Physical Factors Affecting Plasmid DNA Compaction in Stearylamine-Containing Nanoemulsions Intended for Gene Delivery

Cationic lipids have been used in the development of non-viral gene delivery systems as lipoplexes. Stearylamine, a cationic lipid that presents a primary amine group when in solution, is able to compact genetic material by electrostatic interactions. In dispersed systems such as nanoemulsions this...

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Detalles Bibliográficos
Autores principales: Silva, André Leandro, Júnior, Francisco Alexandrino, Verissimo, Lourena Mafra, Agnez-Lima, Lucymara Fassarella, Egito, Lucila Carmem Monte, de Oliveira, Anselmo Gomes, do Egito, Eryvaldo Socrates Tabosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763655/
https://www.ncbi.nlm.nih.gov/pubmed/24281666
http://dx.doi.org/10.3390/ph5060643