Involvement of Multiple Transporters-mediated Transports in Mizoribine and Methotrexate Pharmacokinetics

Mizoribine is administered orally and excreted into urine without being metabolized. Many research groups have reported a linear relationship between the dose and peak serum concentration, between the dose and AUC, and between AUC and cumulative urinary excretion of mizoribine. In contrast, a signif...

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Detalles Bibliográficos
Autores principales: Murakami, Teruo, Mori, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763673/
https://www.ncbi.nlm.nih.gov/pubmed/24280676
http://dx.doi.org/10.3390/ph5080802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763673/
https://www.ncbi.nlm.nih.gov/pubmed/24280676
http://dx.doi.org/10.3390/ph5080802

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