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Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains

The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(ii)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.

Detalles Bibliográficos
Autores principales: Badarau, Adriana, Baslé, Arnaud, Firbank, Susan J., Dennison, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763678/
https://www.ncbi.nlm.nih.gov/pubmed/23926594
http://dx.doi.org/10.1039/c3cc42709a