Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains

The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(ii)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.

Detalles Bibliográficos
Autores principales: Badarau, Adriana, Baslé, Arnaud, Firbank, Susan J., Dennison, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2013
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763678/
https://www.ncbi.nlm.nih.gov/pubmed/23926594
http://dx.doi.org/10.1039/c3cc42709a
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author Badarau, Adriana
Baslé, Arnaud
Firbank, Susan J.
Dennison, Christopher
author_facet Badarau, Adriana
Baslé, Arnaud
Firbank, Susan J.
Dennison, Christopher
author_sort Badarau, Adriana
collection PubMed
description The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(ii)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.
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spelling pubmed-37636782013-09-05 Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains Badarau, Adriana Baslé, Arnaud Firbank, Susan J. Dennison, Christopher Chem Commun (Camb) Chemistry The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(ii)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins. Royal Society of Chemistry 2013-09-21 2013-08-07 /pmc/articles/PMC3763678/ /pubmed/23926594 http://dx.doi.org/10.1039/c3cc42709a Text en This journal is © The Royal Society of Chemistry 2013 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Badarau, Adriana
Baslé, Arnaud
Firbank, Susan J.
Dennison, Christopher
Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains
title Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains
title_full Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains
title_fullStr Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains
title_full_unstemmed Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains
title_short Crosstalk between Cu(i) and Zn(ii) homeostasis via Atx1 and cognate domains
title_sort crosstalk between cu(i) and zn(ii) homeostasis via atx1 and cognate domains
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763678/
https://www.ncbi.nlm.nih.gov/pubmed/23926594
http://dx.doi.org/10.1039/c3cc42709a
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