Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset

Amyotrophic lateral sclerosis is characterized by a progressive degeneration of the corticospinal tract motor neurons. Growing evidence suggests that degeneration may begin at the distal axon proceeding in a dying-back pattern. It seemed therefore of interest to investigate synaptic transmission at...

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Detalles Bibliográficos
Autores principales: Rocha, Mariana C., Pousinha, Paula A., Correia, Alexandra M., Sebastião, Ana M., Ribeiro, Joaquim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764017/
https://www.ncbi.nlm.nih.gov/pubmed/24040091
http://dx.doi.org/10.1371/journal.pone.0073846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764017/
https://www.ncbi.nlm.nih.gov/pubmed/24040091
http://dx.doi.org/10.1371/journal.pone.0073846

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