Distal Loop Flexibility of a Regulatory Domain Modulates Dynamics and Activity of C-Terminal Src Kinase (Csk)

The Src family of tyrosine kinases (SFKs) regulate numerous aspects of cell growth and differentiation and are under the principal control of the C-terminal Src Kinase (Csk). Csk and SFKs share a modular design with the kinase domain downstream of the N-terminal SH2 and SH3 domains that regulate cat...

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Detalles Bibliográficos
Autores principales: Barkho, Sulyman, Pierce, Levi C. T., McGlone, Maria L., Li, Sheng, Woods, Virgil L., Walker, Ross C., Adams, Joseph A., Jennings, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764022/
https://www.ncbi.nlm.nih.gov/pubmed/24039559
http://dx.doi.org/10.1371/journal.pcbi.1003188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764022/
https://www.ncbi.nlm.nih.gov/pubmed/24039559
http://dx.doi.org/10.1371/journal.pcbi.1003188

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