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HDAC1 and HDAC2 Restrain the Intestinal Inflammatory Response by Regulating Intestinal Epithelial Cell Differentiation

Acetylation and deacetylation of histones and other proteins depends on histone acetyltransferases and histone deacetylases (HDACs) activities, leading to either positive or negative gene expression. HDAC inhibitors have uncovered a role for HDACs in proliferation, apoptosis and inflammation. Howeve...

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Detalles Bibliográficos
Autores principales: Turgeon, Naomie, Blais, Mylène, Gagné, Julie-Moore, Tardif, Véronique, Boudreau, François, Perreault, Nathalie, Asselin, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764035/
https://www.ncbi.nlm.nih.gov/pubmed/24040068
http://dx.doi.org/10.1371/journal.pone.0073785