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TRAIL-Deficiency Accelerates Vascular Calcification in Atherosclerosis via Modulation of RANKL

The osteoprotegerin (OPG) and receptor activator of nuclear factor-κB ligand (RANKL) cytokine system, not only controls bone homeostasis, but has been implicated in regulating vascular calcification. TNF–related apoptosis-inducing ligand (TRAIL) is a second ligand for OPG, and although its effect in...

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Detalles Bibliográficos
Autores principales: Di Bartolo, Belinda A., Cartland, Siân P., Harith, Hanis H., Bobryshev, Yuri V., Schoppet, Michael, Kavurma, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764101/
https://www.ncbi.nlm.nih.gov/pubmed/24040204
http://dx.doi.org/10.1371/journal.pone.0074211