Cargando…

Sulphamoylated 2-Methoxyestradiol Analogues Induce Apoptosis in Adenocarcinoma Cell Lines

2-Methoxyestradiol (2ME2) is a naturally occurring estradiol metabolite which possesses antiproliferative, antiangiogenic and antitumor properties. However, due to its limited biological accessibility, synthetic analogues have been synthesized and tested in attempt to develop drugs with improved ora...

Descripción completa

Detalles Bibliográficos
Autores principales: Visagie, Michelle, Theron, Anne, Mqoco, Thandi, Vieira, Warren, Prudent, Renaud, Martinez, Anne, Lafanechère, Laurence, Joubert, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764137/
https://www.ncbi.nlm.nih.gov/pubmed/24039728
http://dx.doi.org/10.1371/journal.pone.0071935