VAPB/ALS8 MSP Ligands Regulate Striated Muscle Energy Metabolism Critical for Adult Survival in Caenorhabditis elegans

Mutations in VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), two motor neuron diseases that often include alterations in energy metabolism. We have shown that C. elegans and Drosophila neurons secrete a cleavage product of VAPB, the N-terminal maj...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Sung Min, El Oussini, Hajer, Scekic-Zahirovic, Jelena, Vibbert, Jack, Cottee, Pauline, Prasain, Jeevan K., Bellen, Hugo J., Dupuis, Luc, Miller, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764199/
https://www.ncbi.nlm.nih.gov/pubmed/24039594
http://dx.doi.org/10.1371/journal.pgen.1003738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764199/
https://www.ncbi.nlm.nih.gov/pubmed/24039594
http://dx.doi.org/10.1371/journal.pgen.1003738

Ejemplares similares