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Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides

Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This switch alters host-microbe interactions and is critical for pathogenicity. However, in zygomycetes, whether dimorphism contributes to virulence is a central unanswered question. The pathogenic zygomycete Mucor...

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Detalles Bibliográficos
Autores principales: Lee, Soo Chan, Li, Alicia, Calo, Silvia, Heitman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764228/
https://www.ncbi.nlm.nih.gov/pubmed/24039585
http://dx.doi.org/10.1371/journal.ppat.1003625