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Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration

Caloric restriction (CR), fasting, and exercise have long been recognized for their neuroprotective and lifespan-extending properties; however, the underlying mechanisms of these phenomena remain elusive. Such extraordinary benefits might be linked to the activation of sirtuins. In mammals, the sirt...

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Detalles Bibliográficos
Autores principales: Kincaid, Brad, Bossy-Wetzel, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764375/
https://www.ncbi.nlm.nih.gov/pubmed/24046746
http://dx.doi.org/10.3389/fnagi.2013.00048