Synthesis and evaluation of a (125)I-labeled iminodihydroquinoline-derived tracer for imaging of voltage-gated sodium channels()

In vivo imaging of voltage-gated sodium channels (VGSCs) can potentially provide insights into the activation of neuronal pathways and aid the diagnosis of a number of neurological diseases. The iminodihydroquinoline WIN17317-3 is one of the most potent sodium channel blockers reported to date and b...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez-Medina, Carlos, Patel, Niral, Robson, Mathew, Lythgoe, Mark F., Årstad, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764405/
https://www.ncbi.nlm.nih.gov/pubmed/23910595
http://dx.doi.org/10.1016/j.bmcl.2013.07.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764405/
https://www.ncbi.nlm.nih.gov/pubmed/23910595
http://dx.doi.org/10.1016/j.bmcl.2013.07.014

Ejemplares similares