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Synthesis and evaluation of a (125)I-labeled iminodihydroquinoline-derived tracer for imaging of voltage-gated sodium channels()
In vivo imaging of voltage-gated sodium channels (VGSCs) can potentially provide insights into the activation of neuronal pathways and aid the diagnosis of a number of neurological diseases. The iminodihydroquinoline WIN17317-3 is one of the most potent sodium channel blockers reported to date and b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764405/ https://www.ncbi.nlm.nih.gov/pubmed/23910595 http://dx.doi.org/10.1016/j.bmcl.2013.07.014 |