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Replication stress-induced alternative mRNA splicing alters properties of the histone RNA-binding protein HBP/SLBP: a key factor in the control of histone gene expression

Animal replication-dependent histone genes produce histone proteins for the packaging of newly replicated genomic DNA. The expression of these histone genes occurs during S phase and is linked to DNA replication via S-phase checkpoints. The histone RNA-binding protein HBP/SLBP (hairpin-binding prote...

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Detalles Bibliográficos
Autores principales: Rattray, Alexander M. J., Nicholson, Pamela, Müller, Berndt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764509/
https://www.ncbi.nlm.nih.gov/pubmed/23941746
http://dx.doi.org/10.1042/BSR20130074