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The apoptotic effects of sirtuin1 inhibitor on the MCF-7 and MRC-5 cell lines

Sirtuin1 (SIRT1) is an enzyme that deacetylates histones and several nonhistone proteins including p53 during stress and plays an important role in the survival of tumor cells. Hereby, this study describes the potency of salermide as a SIRT1 inhibitor to induce apoptosis in the MCF-7 and MRC-5 cell...

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Detalles Bibliográficos
Autores principales: Dastjerdi, M Nikbakht, Salahshoor, M R, Mardani, M, Rabbani, M, Hashemibeni, B, Gharagozloo, M, Kazemi, M, Esmaeil, N, Roshankhah, Sh, Golmohammadi, R, Mobarakian, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764679/
https://www.ncbi.nlm.nih.gov/pubmed/24019817