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Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase

Glycosyltransferases (GTs) are enzymes that are involved, as Nature's “glycosylation reagents,” in many fundamental biological processes including cell adhesion and blood group biosynthesis. Although of similar importance to that of other large enzyme families such as protein kinases and protea...

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Detalles Bibliográficos
Autores principales: Jørgensen, René, Pesnot, Thomas, Lee, Ho Jun, Palcic, Monica M., Wagner, Gerd K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764824/
https://www.ncbi.nlm.nih.gov/pubmed/23836908
http://dx.doi.org/10.1074/jbc.M113.465963