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EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5

BACKGROUND: Tks5/FISH is a scaffold protein comprising of five SH3 domains and one PX domain. Tks5 is a substrate of the tyrosine kinase Src and is required for the organization of podosomes/invadopodia implicated in invasion of tumor cells. Recent data have suggested that a close homologue of Tks5,...

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Detalles Bibliográficos
Autores principales: Fekete, Anna, Bőgel, Gábor, Pesti, Szabolcs, Péterfi, Zalán, Geiszt, Miklós, Buday, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765130/
https://www.ncbi.nlm.nih.gov/pubmed/23924390
http://dx.doi.org/10.1186/1750-2187-8-8