Glycan Elongation Beyond the Mucin Associated Tn Antigen Protects Tumor Cells from Immune-Mediated Killing

Membrane bound mucins are up-regulated and aberrantly glycosylated during malignant transformation in many cancer cells. This results in a negatively charged glycoprotein coat which may protect cancer cells from immune surveillance. However, only limited data have so far demonstrated the critical st...

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Detalles Bibliográficos
Autores principales: Madsen, Caroline B., Lavrsen, Kirstine, Steentoft, Catharina, Vester-Christensen, Malene B., Clausen, Henrik, Wandall, Hans H., Pedersen, Anders Elm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765166/
https://www.ncbi.nlm.nih.gov/pubmed/24039759
http://dx.doi.org/10.1371/journal.pone.0072413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765166/
https://www.ncbi.nlm.nih.gov/pubmed/24039759
http://dx.doi.org/10.1371/journal.pone.0072413

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