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c-Myc Is Essential to Prevent Endothelial Pro-Inflammatory Senescent Phenotype

The proto-oncogene c-Myc is vital for vascular development and promotes tumor angiogenesis, but the mechanisms by which it controls blood vessel growth remain unclear. In the present work we investigated the effects of c-Myc knockdown in endothelial cell functions essential for angiogenesis to defin...

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Detalles Bibliográficos
Autores principales: Florea, Victoria, Bhagavatula, Nithya, Simovic, Gordana, Macedo, Francisco Y., Fock, Ricardo A., Rodrigues, Claudia O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765198/
https://www.ncbi.nlm.nih.gov/pubmed/24039874
http://dx.doi.org/10.1371/journal.pone.0073146