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Interactions between αCaMKII and calmodulin in living cells: conformational changes arising from CaM -dependent and -independent relationships
BACKGROUND: αCaMKII plays central and essential roles in long-term potentiation (LTP), learning and memory. αCaMKII is activated via binding with Ca(2+)/CaM in response to elevated Ca(2+) concentration. Furthermore, prolonged increase in Ca(2+) concentration leads to the auto-phosphorylation of αCaM...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765210/ https://www.ncbi.nlm.nih.gov/pubmed/23958294 http://dx.doi.org/10.1186/1756-6606-6-37 |