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Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors

BACKGROUND: It has been shown that proteasome inhibition leads to growth arrest in the G1 phase of the cell cycle and/or induction of apoptosis. However, it was found that some of these inhibitors do not induce apoptosis in several human normal cell lines. This selective activity makes proteasome in...

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Detalles Bibliográficos
Autores principales: Orabi, Khaled Y, Abaza, Mohamed S, El Sayed, Khalid A, Elnagar, Ahmed Y, Al-Attiyah, Rajaa, Guleri, Radhika P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765228/
https://www.ncbi.nlm.nih.gov/pubmed/23958424
http://dx.doi.org/10.1186/1475-2867-13-82