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Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis

BACKGROUND: Intrapartum administration of single-dose nevirapine (sdNVP) reduces perinatal HIV-1 transmission in resource-limiting settings by half. Yet this strategy has limited effect on subsequent breast milk transmission, making the case for new treatment approaches to extend maternal/infant ant...

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Detalles Bibliográficos
Autores principales: Permar, Sallie R, Salazar, Maria G, Gao, Feng, Cai, Fangping, Learn, Gerald H, Kalilani, Linda, Hahn, Beatrice H, Shaw, George M, Salazar-Gonzalez, Jesus F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765243/
https://www.ncbi.nlm.nih.gov/pubmed/23941304
http://dx.doi.org/10.1186/1742-4690-10-88