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Label-Free Detection of Cu(2+) and Hg(2+) Ions Using Reconstructed Cu(2+)-Specific DNAzyme and G-quadruplex DNAzyme

Label-free metal ion detection methods were developed. To achieve these, a reconstructed Cu(2+)-specific DNA-cleaving DNAzyme (Cu(2+)-specific DNAzyme) with an intramolecular stem-loop structure was used. G-quadruplex-forming G-rich sequence(s), linked at the ends of double-helix stem of an intramol...

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Detalles Bibliográficos
Autores principales: Li, Hui, Huang, Xiao-Xi, Cai, Yang, Xiao, Hao-Jie, Zhang, Qiu-Fen, Kong, De-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765245/
https://www.ncbi.nlm.nih.gov/pubmed/24039849
http://dx.doi.org/10.1371/journal.pone.0073012