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In Silico Mechanistic Profiling to Probe Small Molecule Binding to Sulfotransferases
Drug metabolizing enzymes play a key role in the metabolism, elimination and detoxification of xenobiotics, drugs and endogenous molecules. While their principal role is to detoxify organisms by modifying compounds, such as pollutants or drugs, for a rapid excretion, in some cases they render their...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765257/ https://www.ncbi.nlm.nih.gov/pubmed/24039991 http://dx.doi.org/10.1371/journal.pone.0073587 |