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Lipopolysaccharide-Induced Weakness in the Preterm Diaphragm Is Associated with Mitochondrial Electron Transport Chain Dysfunction and Oxidative Stress

Diaphragmatic contractility is reduced in preterm lambs after lipopolysaccharide (LPS) exposure in utero. The mechanism of impaired fetal diaphragm contractility after LPS exposure is unknown. We hypothesise that in utero exposure to LPS induces a deficiency of mitochondrial complex activity and oxi...

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Detalles Bibliográficos
Autores principales: Song, Yong, Pinniger, Gavin J., Bakker, Anthony J., Moss, Timothy J. M., Noble, Peter B., Berry, Clare A., Pillow, Jane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765262/
https://www.ncbi.nlm.nih.gov/pubmed/24039949
http://dx.doi.org/10.1371/journal.pone.0073457