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Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) is the limiting enzyme in one of pathways of synthesis of Nicotinamide Adenine Dinucleotide, a redox coenzyme. NAMPT is considered as an insulin-mimetic factor and a potential regulatory factor in inflammatory and immune processes. Associati...

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Detalles Bibliográficos
Autores principales: Saddi-Rosa, Pedro, Oliveira, Carolina Soares, Crispim, Felipe, Giuffrida, Fernando MA, de Lima, Valter Correia, Vieira, José Gilberto, Doria, Alessandro, Velho, Gilberto, Reis, André Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765274/
https://www.ncbi.nlm.nih.gov/pubmed/23968400
http://dx.doi.org/10.1186/1475-2840-12-119