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Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice

BACKGROUND: Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is caused by a 1.5-3 Mb microdeletion of chromosome 22q11.2, frequently referred to as 22q11.2 deletion syndrome (22q11DS). This region includes TBX1, a T-box transcription factor gene that contributes to the etiology of 22q11DS. T...

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Detalles Bibliográficos
Autores principales: Freyer, Laina, Nowotschin, Sonja, Pirity, Melinda K, Baldini, Antonio, Morrow, Bernice E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765320/
https://www.ncbi.nlm.nih.gov/pubmed/23971992
http://dx.doi.org/10.1186/1471-213X-13-33