Myc-Dependent Genome Instability and Lifespan in Drosophila

The Myc family of transcription factors are key regulators of cell growth and proliferation that are dysregulated in a large number of human cancers. When overexpressed, Myc family proteins also cause genomic instability, a hallmark of both transformed and aging cells. Using an in vivo lacZ mutation...

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Detalles Bibliográficos
Autores principales: Greer, Christina, Lee, Moonsook, Westerhof, Maaike, Milholland, Brandon, Spokony, Rebecca, Vijg, Jan, Secombe, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765364/
https://www.ncbi.nlm.nih.gov/pubmed/24040302
http://dx.doi.org/10.1371/journal.pone.0074641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765364/
https://www.ncbi.nlm.nih.gov/pubmed/24040302
http://dx.doi.org/10.1371/journal.pone.0074641

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