Disruption of Glycerol Metabolism by RNAi Targeting of Genes Encoding Glycerol Kinase Results in a Range of Phenotype Severity in Drosophila

In Drosophila, RNAi targeting of either dGyk or dGK can result in two alternative phenotypes: adult glycerol hypersensitivity or larval lethality. Here we compare these two phenotypes at the level of glycerol kinase (GK) phosphorylation activity, dGyk and dGK-RNA expression, and glycerol levels. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Wightman, Patrick J., Jackson, George R., Dipple, Katrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765373/
https://www.ncbi.nlm.nih.gov/pubmed/24039719
http://dx.doi.org/10.1371/journal.pone.0071664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765373/
https://www.ncbi.nlm.nih.gov/pubmed/24039719
http://dx.doi.org/10.1371/journal.pone.0071664

Ejemplares similares