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Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore

BACKGROUND: Global hypomethylation of repetitive DNA sequences is believed to occur early in tumorigenesis. There is a great interest in identifying factors that contribute to global DNA hypomethylation and associated cancer risk. We tested the hypothesis that plasma S-adenosylmethionine (SAM) level...

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Detalles Bibliográficos
Autores principales: Inoue-Choi, Maki, Nelson, Heather H, Robien, Kim, Arning, Erland, Bottiglieri, Teodoro, Koh, Woon-Puay, Yuan, Jian-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765398/
https://www.ncbi.nlm.nih.gov/pubmed/23957506
http://dx.doi.org/10.1186/1471-2407-13-389