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Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore
BACKGROUND: Global hypomethylation of repetitive DNA sequences is believed to occur early in tumorigenesis. There is a great interest in identifying factors that contribute to global DNA hypomethylation and associated cancer risk. We tested the hypothesis that plasma S-adenosylmethionine (SAM) level...
Autores principales: | Inoue-Choi, Maki, Nelson, Heather H, Robien, Kim, Arning, Erland, Bottiglieri, Teodoro, Koh, Woon-Puay, Yuan, Jian-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765398/ https://www.ncbi.nlm.nih.gov/pubmed/23957506 http://dx.doi.org/10.1186/1471-2407-13-389 |
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