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Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

BACKGROUND: RTS,S is the most advanced candidate malaria vaccine but it is only partially protective and the causes of inter-individual variation in efficacy are poorly understood. Here, we investigated whether peripheral blood monocyte-to-lymphocyte ratios (ML ratio), previously shown to correlate...

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Detalles Bibliográficos
Autores principales: Warimwe, George M, Fletcher, Helen A, Olotu, Ally, Agnandji, Selidji T, Hill, Adrian VS, Marsh, Kevin, Bejon, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765422/
https://www.ncbi.nlm.nih.gov/pubmed/23962071
http://dx.doi.org/10.1186/1741-7015-11-184