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Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data
BACKGROUND: RTS,S is the most advanced candidate malaria vaccine but it is only partially protective and the causes of inter-individual variation in efficacy are poorly understood. Here, we investigated whether peripheral blood monocyte-to-lymphocyte ratios (ML ratio), previously shown to correlate...
Autores principales: | Warimwe, George M, Fletcher, Helen A, Olotu, Ally, Agnandji, Selidji T, Hill, Adrian VS, Marsh, Kevin, Bejon, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765422/ https://www.ncbi.nlm.nih.gov/pubmed/23962071 http://dx.doi.org/10.1186/1741-7015-11-184 |
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