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Telomere length dynamics in human memory T cells specific for viruses causing acute or latent infections

BACKGROUND: Declining telomere length (TL) is associated with T cell senescence. While TL in naïve and memory T cells declines with increasing age, there is limited data on TL dynamics in virus-specific memory CD4(+) T cells in healthy adults. We combined BrdU-labeling of virus-stimulated T cells fo...

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Detalles Bibliográficos
Autores principales: O'Bryan, Joel M, Woda, Marcia, Co, Mary, Mathew, Anuja, Rothman, Alan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765437/
https://www.ncbi.nlm.nih.gov/pubmed/23971624
http://dx.doi.org/10.1186/1742-4933-10-37