Engineering Yeast Hexokinase 2 for Improved Tolerance Toward Xylose-Induced Inactivation

Hexokinase 2 (Hxk2p) from Saccharomyces cerevisiae is a bi-functional enzyme being both a catalyst and an important regulator in the glucose repression signal. In the presence of xylose Hxk2p is irreversibly inactivated through an autophosphorylation mechanism, affecting all functions. Consequently,...

Descripción completa

Detalles Bibliográficos
Autores principales: Bergdahl, Basti, Sandström, Anders G., Borgström, Celina, Boonyawan, Tarinee, van Niel, Ed W. J., Gorwa-Grauslund, Marie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765440/
https://www.ncbi.nlm.nih.gov/pubmed/24040384
http://dx.doi.org/10.1371/journal.pone.0075055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765440/
https://www.ncbi.nlm.nih.gov/pubmed/24040384
http://dx.doi.org/10.1371/journal.pone.0075055

Ejemplares similares