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Whole transcriptome RNA-Seq allelic expression in human brain

BACKGROUND: Measuring allelic RNA expression ratios is a powerful approach for detecting cis-acting regulatory variants, RNA editing, loss of heterozygosity in cancer, copy number variation, and allele-specific epigenetic gene silencing. Whole transcriptome RNA sequencing (RNA-Seq) has emerged as a...

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Detalles Bibliográficos
Autores principales: Smith, Ryan M, Webb, Amy, Papp, Audrey C, Newman, Leslie C, Handelman, Samuel K, Suhy, Adam, Mascarenhas, Roshan, Oberdick, John, Sadee, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765493/
https://www.ncbi.nlm.nih.gov/pubmed/23968248
http://dx.doi.org/10.1186/1471-2164-14-571